Patients underwent MRI at four points: before treatment (T0), early treatment (T1), interregimen (T2), and before surgery (T3).
Alex p. nguyen oncology consultants pa serial#
Materials and Methods A retrospective review was performed for women with menopausal status data who were treated for breast cancer by one of 10 drug arms (standard NAC with or without experimental agents) between May 2010 and November 2016 in the Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging and Molecular Analysis 2, or I-SPY 2 TRIAL ( NCT01042379). Purpose To investigate the relationship between lack of BPE suppression and pathologic response.
It was hypothesized that nonsuppressed BPE may be associated with inferior response to NAC.
Joseph's Women's Hospital, Tampa, Fla (J.D.) Department of Radiology, Emory University, Atlanta, Ga (M.S.N.) Department of Radiology, Mayo Clinic Arizona, Phoenix, Ariz (M.E.G.) Department of Radiology, Inova Health System, Fairfax, Va (E.B.) Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston, Mass (C.D.L.) Department of Radiology, University of Washington, Seattle, Wash (S.C.P.) Department of Medical Imaging, Banner University Medical Center Tucson, Tucson, Ariz (K.A.F., M.H.B.) Department of Radiology, University of Texas MD Anderson Cancer Center, Houston, Tex (W.T.Y., B.D.) Department of Radiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Tex (B.D., S.H.G.) Department of Radiology, University of Michigan, Ann Arbor, Mich (T.C.) Department of Surgery, University of California San Francisco, San Francisco, Calif (C.Y., L.J.E.) Department of Oncology and Hematology, University of Pennsylvania, Philadelphia, Pa (A.D.) and Berry Consultants, LLC, Austin, Tex (D.A.B.).īackground Suppression of background parenchymal enhancement (BPE) is commonly observed after neoadjuvant chemotherapy (NAC) at contrast-enhanced breast MRI. 1 Author affiliations: From the Department of Radiology & Biomedical Imaging, University of California San Francisco, 1600 Divisadero St, Room C255, San Francisco, CA 94115 (N.O., W.L., D.C.N., R.J.H., F.S., A.A.T.N., V.A.A., J.G., E.F.J., L.J.W., B.N.J., E.R.P., N.M.H.) Department of Breast Radiology, Karolinska University Hospital, Solna, Stockholm, Sweden (F.S.) Department of Radiology, Kaiser Permanente Vallejo Medical Center, Vallejo, Calif (V.A.A.) Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, Calif (J.K.) Department of Radiology, University of California San Diego, La Jolla, Calif (H.O.F., M.E.) Department of Radiology, The University of Alabama at Birmingham, Birmingham, Ala (K.W.Z., S.W., H.R.U.) Department of Radiology, University of Minnesota, Minneapolis, Minn (M.T.N., A.L.C., P.J.B.) Department of Radiology, Loyola Medicine, Maywood, Ill (T.K., K.W., K.M.) Department of Radiology, University of Colorado Denver, Denver, Colo (D.W., K.F., D.L.P., L.H.) Department of Diagnostic Radiology, Mayo Clinic Rochester, Rochester, Minn (K.R.B.) Department of Radiology, University of Pennsylvania, Philadelphia, Pa (E.S.M., M.R., D.K.) Department of Radiology, University of Chicago Medical Center, Chicago, Ill (H.A., D.S.) Department of Radiology, Georgetown University, Washington, DC (E.C., C.D.) Department of Radiology, University of Southern California, Los Angeles, Calif (P.S., L.H.L.) Department of Radiology, Swedish Cancer Institute, Seattle, Wash (D.H.B., B.P.) Department of Radiology, Oregon Health & Science University, Portland, Ore (K.Y.O., N.J., L.A.T.) Department of Radiology, Moffitt Cancer Center, Tampa, Fla (B.N., J.D.) Department of Women's Imaging, St.
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